Diffusion appears to be affected by dilution and dose, butnot by molecular weight, complex size, or the presence of complexing proteins. 2008 ); andinhibition of all downstream enzymes ( i.e.,cyclo-oxygenase, lipoxygenase, and cytochrome P450)is required for effective protection, suggestingcomplex overlapping function (Miyahara et al.2008). [11], all hematoge-nous episodes were monomicrobial. The cortex forms the outerportion ofthe node except at the hilum. 1990),and distal airway pressures vary in responseto changes of the ratio of inspiratory to expira-tory time (I/E ratio) during HFOV.

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In the newborn (topright) the Vr is low in comparison with that of the adult.The neonate actively maintains an EEV above Vr. However,the potential adverse effects of PEEP on cardio-vascular function mean that the most importanttherapeutic goal is the level of PEEP that gives thebest combination of oxygenation and cardiac out-put, thereby achieving maximum oxygen delivery(oxygen content x cardiac output)

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